Quarterback
Biggest Winner: Matthew Stafford (Rams)
Stafford made history on Sunday by becoming the first quarterback in NFL history to throw 4 TD's and 0 INT's in 3 straight games with the gem that he spun (280 YDS, 4 TD's) in a dominant divisional win over the 49ers. This remarkable streak will likely come to an end this week against a frisky Seahawks defense that is on a heater right now, but their secondary is vulnerable enough to keep Stafford in high-end QB1 territory.
Honorable Mentions: Jaxson Dart (Giants), Caleb Williams (Bears), Jared Goff (Lions)
Biggest Loser: Bo Nix (Broncos)
There was no 4th quarter magic to atone for an otherwise poor performance from Nix this week as the Broncos QB put together one of the worst performances (150 YDS/TD/2 INT, -2 Rushing YDS) of his largely ugly sophomore season in a terrific matchup with the lowly Raiders. Nix will be a really risky starting option for this week's huge showdown with the Chiefs.
Dishonorable Mentions: Jalen Hurts (Eagles), Jordan Love (Packers), Justin Herbert (Chargers)
Running Back
Biggest Winner: Jonathan Taylor (Colts)
Just when you think Taylor couldn't possibly keep one-upping himself during his magical 2025 campaign, he goes ahead and does it again. The Colts star back was completely unstoppable (32 CAR/244 YDS/3 TD's, 3 REC/42 YDS) as he carried the Colts to a thrilling OT win over the Falcons in Berlin. Taylor's fantasy owners will be scrambling for a replacement as the current runaway frontrunner for fantasy MVP gets a well-deserved rest as the Colts head into their Week 11 bye.
Honorable Mentions: De'Von Achane (Dolphins), Jahmyr Gibbs (Lions), TreVeyon Henderson (Patriots)
Biggest Loser: Jacory Croskey-Merritt (Commanders)
The Lions tough run D and the Marcus Mariota-led Commanders getting bulldozed from start to finish made Croskey-Merritt pretty much useless for fantasy purposes as he turned his 11 carries into just 30 YDS. Croskey-Merritt will be an RB3 for this week's sure-to-be thrilling matchup with the Dolphins in Madrid.
Dishonorable Mentions: Jordan Mason (Vikings), R.J. Harvey (Broncos), Chuba Hubbard (Panthers)
Wide Receiver
Biggest Winner: Drake London (Falcons)
While it wasn't quite as dominant as his Week 9 performance against the Patriots, London once again shined bright in a heartbreaking Falcons loss-hauling in 6 receptions for 104 YDS and a TD while further boosting his statline with a 2 PT-CNV grab against the Colts. London will have revenge on the brain this week when he goes up against a Panthers secondary that held him to 55 scoreless YDS during their previous meeting in Week 3.
Honorable Mentions: Jameson Williams (Lions), Emeka Egbuka (Buccaneers), Nico Collins (Texans)
Biggest Loser: A.J. Brown (Eagles)
Brown's shockingly quiet 2025 continued in Green Bay last night as he caught 2-of-3 targets for 13 YDS in a defensive slugfest that saw DeVonta Smith, Saquon Barkley and Dallas Goedert serve as the primary beneficiaries of Jalen Hurts' limited passing production. The next stop on Brown's current boom-or-bust tour is a home date with a banged-up Lions secondary that has held up surprisingly well over the last few games.
Dishonorable Mentions: Courtland Sutton (Broncos), Michael Pittman Jr. (Colts), D.J. Moore (Bears)
Tight End
Biggest Winner: Trey McBride (Cardinals)
Early garbage time for the Cardinals in a wire-to-wire shellacking carried out by the menacing hands of the Seahawks meant plenty of opportunities for McBride to run his numbers up. In fact, Jacoby Brissett's favorite target ended up having his most productive game of the season-ripping off 127 YDS and a TD on his 9 receptions. McBride will look to extend his career-best 4-game TD streak against the 49ers on Sunday.
Honorable Mentions: George Kittle (49ers), Tyler Warren (Colts), Juwan Johnson (Saints)
Biggest Loser: Brock Bowers (Raiders)
Facing a short week and dealing away Jakobi Meyers to the Jaguars on Tuesday meant the Raiders were going to be leaning even heavier on Bowers than usual. The Broncos knew this too and effectively removed him from the game, holding the star TE to just 2 total touches (a 31-YD reception, a -4-YD carry) in one of the least compelling games of the year so far. Bowers' stint in the fantasy doghouse should be short-lived as he'll have an excellent opportunity to feast in Week 11 when he goes up against the Cowboys porous defense.
Dishonorable Mentions: T.J. Hockenson (Vikings), Hunter Henry (Patriots), Kyle Pitts (Falcons)
Defense/Special Teams
Biggest Winner: Seahawks
A big part of why garbage time came early for the Cardinals on Sunday was the play of the Seahawks defense. The 'Hawks brought hellfire down on the Cards offense, picking up 5 sacks and a pair of fumble recovery TD's from DeMarcus Lawrence in a 44-22 victory. This upstart group will have a much tougher task in front of them this week when they're asked to try and slow down a scorching hot Rams offense in their building.
Honorable Mentions: Chargers, Texans, Broncos
Biggest Loser: Lions
This wasn't a horrible performance by the Lions defense, it was just an unremarkable one given that an already vulnerable Commanders offense was forced to trot out their backup QB. Kelvin Sheppard's troops got 2 sacks and forced zero turnovers in an easy 44-22 victory over an injury-depleted squad that looks nothing like the team that bounced them from the playoffs in January. They'll draw a total wild card assignment in Week 11 when they head east to Philly to take on a comically erratic Eagles offense.
Dishonorable Mentions: Bills, Browns, Patriots
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